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May aid bedside asynchrony detection; leaves open prospective validation against contemporary imaging.
Asynchrony of ventricular contraction causes splitting of the first and second heart sounds which can be detected clinically in most normal subjects, and deviations from normal due to electrical or mechanical delays on one or other side of the heart have received much attention as valuable physical signs and in the understanding of hxmodynamics.
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Haber et al. (1965) studied this question.
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