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February 8, 1999Biochemical JournalOpen Access

Evidence for the involvement of p59fyn and p53/56lyn in collagen receptor signalling in human platelets

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SBStephen J. BriddonUniversity of NottinghamSWSteve P. WatsonVascular Medicine

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Briddon et al. (1999) studied this question.

synapsesocial.com/papers/6a20cd820c5283fd3a1b59f2https://doi.org/10.1042/bj3380203
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Interactions of Lyn with the antigen receptor during B cell activation.1994 · 65 citations
  2. 2Platelets with 10% of the normal amount of glycoprotein VI have an impaired response to collagen that results in a mild bleeding tendency1995 · 159 citations
  3. 3p59 fyn Tyrosine Kinase Associates with Multiple T-Cell Receptor Subunits through Its Unique Amino-Terminal Domain1992 · 58 citations
  4. 4Collagen stimulates tyrosine phosphorylation of phospholipase C‐γ2 but not phospholipase C‐γ1 in human platelets1994 · 139 citations
  5. 5Integrin α2β1-independent activation of platelets by simple collagen-like peptides: collagen tertiary (triple-helical) and quaternary (polymeric) structures are sufficient alone for α2β1-independent platelet reactivity1995 · 324 citations