Why the study?
Does increased use of evidence-based medications (fibrinolytics, aspirin, beta-blockers, ACE inhibitors) reduce 5-year mortality in patients discharged alive after acute myocardial infarction?
Population
2,188 patients discharged alive after hospitalization for acute myocardial infarction in Göteborg.
Comparison
Medical management during 1990-1991… vs Medical management during 1986-1987…
Design
Cohort
Follow-up
5 years
Authors
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Supports association of greater evidence-based therapy use with lower post-MI mortality; leaves open causal effects in observational data.
Does increased use of evidence-based medications (fibrinolytics, aspirin, beta-blockers, ACE inhibitors) reduce 5-year mortality in patients discharged alive after acute myocardial infarction?
Increased utilization of evidence-based therapies, including fibrinolytics, aspirin, beta-blockers, and ACE inhibitors, after acute myocardial infarction is associated with a significant reduction in 5-year mortality, particularly in patients without a history of heart failure.
Herlitz et al. (2001) studied this question.
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