Key result
Depression in women acts as a complex, bidirectional risk factor for incident cardiovascular disease, with important sex differences affecting both incidence and clinical outcomes.
This review highlights the complex, bidirectional relationship between depression and cardiovascular disease in women, emphasizing the need to understand sex differences to guide treatment and research.
Supports integrated depression-CVD screening in women; leaves open sex-specific interventional trials.
The importance of mind-body health relationships has been recognized for decades, but only recently has the wider medical and cardiovascular community become engaged in understanding and addressing the complex, bidirectional risk relationship between cardiovascular disease (CVD) and depression. Furthermore, it has become increasingly clear that there are incompletely understood sex differences in incidence and outcomes for both conditions that should guide treatment and future research efforts. This review will explore the role of depression in women as a risk factor for incident CVD, its impact on women already suffering from CVD, proposed psychobiologic mechanisms and links, and the implications of sex differences on diagnosis and treatment.
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Sharonne N. Hayes (2009) conducted a review in Depression and Cardiovascular Disease. Depression was evaluated. Depression in women acts as a complex, bidirectional risk factor for incident cardiovascular disease, with important sex differences affecting both incidence and clinical outcomes.
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