Why the study?
Depression is linked to increased morbidity and death in cardiovascular disease, with evidence suggesting a reciprocal relationship and high comorbidity impacting long-term outcomes.
This review emphasizes the bidirectional relationship between depression and cardiovascular disease, advocating for a multimodal therapeutic approach.
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May support integrated depression screening in CVD care; leaves open optimal multimodal intervention trials.
Wu et al. (2026) studied this question.
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