What question did this study set out to answer?

This study aims to compare brain atrophy rates in patients with dementia subtypes using MRI assessments.

May 22, 2001Neurology

Progressive brain atrophy on serial MRI in dementia with Lewy bodies, AD, and vascular dementia

View Full Paper

Ask AI

Bookmark

Authors

Randomized trial measures brain atrophy rates in dementia types, indicating early diagnosis is crucial.

This study aims to compare brain atrophy rates in patients with dementia subtypes using MRI assessments.
Participants included 10 DLB patients, 9 AD patients, 9 VaD patients, and 20 controls.
Brain atrophy rates were assessed using the boundary shift integral on serial MRI scans.
Statistical comparisons were made between dementia groups and controls.
DLB had a mean atrophy rate of 1.4% per year, AD had 2.0%, VaD had 1.9%, and controls had 0.5%.
Dementia subjects exhibited higher atrophy rates compared to controls (p < 0.001).
No significant differences in atrophy rates were observed among the three dementia groups.

O’Brien et al. (2001) studied this question.

View Full Paper

Ask AI

Bookmark