A number of methods of synthesis of methanol labelled with 18 O or with 17 O have been evaluated. The best method is considered to be the partial hydrolysis of trimethyl phosphate. Ethanol‐ 18 O can be prepared analogously by the partial hydrolysis of triethyl phosphate. The most accurate method for the isotopic analysis of oxygen in methanol is by pyrolysis in a specially designed vessel, the hydrogen being extracted through a palladium tube and the residual carbon monoxide analysed mass‐spectrometrically.
No takes yet. Share an insight, caveat, or question.
Borowitz et al. (1965) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: