Why the study?
How do beta-adrenoceptor antagonists affect blood flow to the jeopardized myocardium in patients with angina pectoris?
Population
Patients with angina pectoris and coronary artery stenosis (jeopardized myocardium)
Design
Review
Authors
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May aid endocardial salvage in angina; leaves open randomized confirmation of clinical benefit.
How do beta-adrenoceptor antagonists affect blood flow to the jeopardized myocardium in patients with angina pectoris?
Beyond reducing myocardial oxygen demand, beta-blockers improve endocardial perfusion in ischemic myocardium, contributing to the salvage of jeopardized tissue.
P. R. Saxena (1983) studied this question.
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