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August 31, 2022Journal of Hematology & OncologyOpen Access

Treatment of myelodysplastic syndromes in the era of precision medicine and immunomodulatory drugs: a focus on higher-risk disease

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Authors

RMRazan MohtyRHRama Al HamedABAli Bazarbachi

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Overview

Review explores advances in treating higher-risk myelodysplastic syndromes, highlighting potential therapies.

Key Points

  • This research aims to summarize recent advancements in the treatment of higher-risk myelodysplastic syndromes (MDS).
  • Review of recent literature on MDS treatment advancements.
  • Focus on targeted and immune therapies for higher-risk MDS.
  • Discussion of the role of molecular and genetic characterizations in therapy development.
  • Novel therapies show promise for MDS but need further exploration.
  • Genetic insights into MDS are expanding treatment options.
  • Potential for targeted and immune therapies remains to be fully defined.

Cite This Study

Mohty et al. (2022) studied this question.

synapsesocial.com/papers/6a20d73834bef10fdaeb0d60https://doi.org/10.1186/s13045-022-01346-9
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Randomized Phase II Study of Azacitidine Alone or in Combination With Lenalidomide or With Vorinostat in Higher-Risk Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia: North American Intergroup Study SWOG S11172017 · 239 citations
  2. 2Molecular International Prognostic Scoring System for Myelodysplastic Syndromes2022 · 863 citations
  3. 3Hereditary Predispositions to Myelodysplastic Syndrome2016 · 73 citations
  4. 4A randomized controlled trial of romiplostim in patients with low- or intermediate-risk myelodysplastic syndrome receiving decitabine2012 · 81 citations
  5. 5Ipilimumab for Patients with Relapse after Allogeneic Transplantation2016 · 602 citations