Why the study?
Does ergonovine maleate induce coronary artery spasm in patients with idiopathic mitral valve prolapse syndrome and chest pain?
Does ergonovine maleate induce coronary artery spasm in patients with idiopathic mitral valve prolapse syndrome and chest pain?
Ergonovine-induced coronary artery spasm is absent in the majority of patients with idiopathic mitral valve prolapse syndrome and chest pain, suggesting it is not the primary mechanism for their symptoms.
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Negative ergonovine testing in most mitral valve prolapse patients with chest pain; hypothesis-generating against spasm as primary mechanism, needing larger prospective studies.
Sabom et al. (1978) studied this question.
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