Key result
Left temporal lobe epilepsy is associated with increased cardiac vagal tone compared to right temporal lobe epilepsy, evidenced by a significantly decreased LF/HF ratio (p < 0.0001) and increased high-frequency values.
Why the study?
The temporal lobe regulates autonomic cardiovascular functions, and this study aimed to compare HRV changes between TLE patients with right versus left epileptic foci.
Does the lateralization of temporal lobe epilepsy (left vs. right) affect cardiac autonomic control as measured by heart rate variability?
Population
Fifty-two adult patients with TLE
Comparison
Right TLE vs left TLE epileptic foci
Design
Observational cross-sectional study
Authors
Loading...
Association supports lateralized autonomic control in TLE; hypothesis-generating for differential arrhythmia risk.
Observational (n=52)
Yes
Does the lateralization of temporal lobe epilepsy (left vs. right) affect cardiac autonomic control as measured by heart rate variability?
p-value: p=<0.0001
Left temporal lobe epilepsy is associated with increased cardiac vagal tone compared to right temporal lobe epilepsy, suggesting lateralized cardiac autonomic control and potentially lower susceptibility to cardiac dysfunctions.
Dono et al. (2020) conducted an observational in Temporal Lobe Epilepsy (n=52). Left temporal lobe epilepsy (L-TLE) vs. Right temporal lobe epilepsy (R-TLE) was evaluated on Low frequency/high-frequency (LF/HF) ratio (p=<0.0001). Left temporal lobe epilepsy is associated with increased cardiac vagal tone compared to right temporal lobe epilepsy, evidenced by a significantly decreased LF/HF ratio (p < 0.0001) and increased high-frequency values.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: