Key result
Cellular expression of cavin-1 and caveolin-1 on adipocytes was tightly related to cell surface area (mean coefficient of regression 0.83 and 0.77, respectively).
Effect estimate: mean coefficient of regression 0.83 for cavin and 0.77 for caveolin
Caveolar density in adipocytes is tightly related to cell surface area within individuals but decreases with increasing animal age.
No takes yet. Share an insight, caveat, or question.
Adipocyte caveolar scaling in rodents warrants no clinical action; leaves open human metabolic relevance.
Hulstrøm et al. (2013) studied this question. Age and adipocyte size was evaluated on Relation between adipocyte size and cellular expression of caveolar proteins (cavin-1 and caveolin-1) (mean coefficient of regression 0.83 for cavin and 0.77 for caveolin). Cellular expression of cavin-1 and caveolin-1 on adipocytes was tightly related to cell surface area (mean coefficient of regression 0.83 and 0.77, respectively).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: