Key result
Cardiac autonomic modulation exhibited a significant circadian rhythm (p<0.0001 for all HRV indices), with older age associated with lower mean HRV and males showing higher oscillation amplitude.
Population
115 non-smoking community-dwelling individuals, mean age 56, 63% female, 76% white.
Design
Cross-sectional
Follow-up
24 hours
Authors
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Age- and sex-specific HRV circadian patterns are hypothesis-generating; prospective studies needed before clinical consideration.
Observational (n=115)
No
p-value: p=<0.0001
The circadian pattern of cardiac autonomic modulation can be quantified by cosine parameters of HRV, which vary significantly with age and gender.
Li et al. (2011) conducted an observational in Healthy (n=115). Circadian time was evaluated on Circadian variation of HRV indices (zero amplitude test) (p=<0.0001). Cardiac autonomic modulation exhibited a significant circadian rhythm (p<0.0001 for all HRV indices), with older age associated with lower mean HRV and males showing higher oscillation amplitude.
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