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November 6, 2003European Journal of Cardio-Thoracic SurgeryOpen Access

Re-operation for bioprosthetic aortic structural failure – risk assessment

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Key result

Re-operation for bioprosthetic aortic structural failure in patients with NYHA class IV symptoms was associated with significantly higher mortality (OR 7.8, P=0.0082).

Authors

WJW.R. Eric Jamieson

Discussion

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Overview

NYHA IV symptoms warrant heightened risk counseling before reoperation; leaves open whether earlier intervention improves survival in bioprosthetic failure.

Study Design

Type

Cohort (n=3,356)

PICO

P
Population
3,356 patients who received a heterograft bioprosthesis between 1975 and 1999, of whom 312 underwent 322 re-operations for structural valve deterioration.
E
Exposure / Comparator
NYHA class IV at re-operation vs NYHA class I/II
O
Primary Outcome
Mortality — OR 7.8, p=0.0082

Main Result

Odds Ratio: 7.8

Absolute Event Rate: 16% vs 2%

p-value: p=0.0082

Cite This Study

W.R. Eric Jamieson (2003) conducted a cohort in Bioprosthetic aortic structural failure (n=3,356). NYHA class IV at re-operation vs. NYHA class I/II was evaluated on Mortality (OR 7.8, p=0.0082). Re-operation for bioprosthetic aortic structural failure in patients with NYHA class IV symptoms was associated with significantly higher mortality (OR 7.8, P=0.0082).

synapsesocial.com/papers/6a20db34e72f0fa382ecb55bhttps://doi.org/10.1016/s1010-7940(03)00566-9
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