Key result
Cardiac resynchronization therapy successfully treated a case of acute rate-dependent LBBB-associated cardiomyopathy with recurrent systolic heart failure and flash pulmonary edema.
Case Report (n=1)
Cardiac resynchronization therapy can successfully treat acute rate-dependent LBBB-associated cardiomyopathy presenting with recurrent flash pulmonary edema.
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Supports CRT consideration in select refractory cases; hypothesis-generating for broader rate-dependent LBBB cardiomyopathy populations.
Left bundle branch block (LBBB) is an electrophysiological abnormality that can have profound acute and chronic hemodynamic effects.1 Intermittent LBBB has been noted to occur with accelerations in heart rate, typically during exercise (known as rate-dependent LBBB). This has been associated with acute deteriorations in cardiac systolic function through the development of left ventricular (LV) dyssynchrony, and also episodic chest pain (“painful LBBB syndrome”).2–4 We present a case of an acute rate-dependent LBBB-associated cardiomyopathy with recurrent episodes of systolic heart failure and “flash” pulmonary edema that was successfully treated with cardiac resynchronization therapy (CRT).
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Tan et al. (2016) conducted a case report in Acute rate-dependent LBBB-associated cardiomyopathy (n=1). Cardiac resynchronization therapy (CRT) was evaluated. Cardiac resynchronization therapy successfully treated a case of acute rate-dependent LBBB-associated cardiomyopathy with recurrent systolic heart failure and flash pulmonary edema.
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