Why the study?
Does acutely ischemic myocardium maintain contractile behavior and respond to inotropic agents in pig and dog models?
Does acutely ischemic myocardium maintain contractile behavior and respond to inotropic agents in pig and dog models?
Acutely ischemic myocardium retains contractile behavior and responsiveness to inotropic agents, which can be quantified using force-velocity relationships.
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Should not guide clinical decisions in acute ischemia; leaves open human translation of preserved myocardial mechanics from animal models.
Hood et al. (1969) studied this question.
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