What is the clinical evidence from this study?

Study design: Cohort. Population: Aortic root aneurysm and aortic insufficiency (n=374). Intervention: Aortic valve sparing operations. Primary outcome: Overall survival at 20 years.

January 1, 2013

Aortic valve sparing operations demonstrated excellent long-term durability, with an overall survival of 69.3% and freedom from reoperation of 94.2% at 20 years.

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Population

Patients undergoing aortic valve sparing operations at a single institution

Design

Case_series

Follow-up

20 years

Key result

Aortic valve sparing operations demonstrated excellent long-term durability, with an overall survival of 69.3% and freedom from reoperation of 94.2% at 20 years.

Authors

TDTirone E. David

Discussion

Member takes

Overview

Supports aortic valve sparing durability in selected patients; single-center data leaves generalizability open.

Study Design

Type

Cohort (n=374)

Multicenter

Structured PICO

Population

374 consecutive patients undergoing aortic valve sparing operations (reimplantation or remodeling) for aortic root aneurysm or insufficiency, followed for a mean of 7.2 years.

Intervention

Aortic valve sparing operations (reimplantation of the aortic valve and remodeling of the aortic root)

Outcome

Clinical outcomes at 20 years

This presentation summarizes a 20-year single-center clinical experience with aortic valve sparing operations.

Limitations

Single-center observational design
Potential selection bias in the choice between reimplantation and remodeling procedures
Lack of statistical power to detect significant differences in late aortic insufficiency between techniques

Cite This Study

Tirone E. David (2013) conducted a cohort in Aortic root aneurysm and aortic insufficiency (n=374). Aortic valve sparing operations was evaluated on Overall survival at 20 years. Aortic valve sparing operations demonstrated excellent long-term durability, with an overall survival of 69.3% and freedom from reoperation of 94.2% at 20 years.

synapsesocial.com/papers/6a20e0c7dc4e16663149d236 https://doi.org/10.3978/j.issn.2225-319x.2012.11.15

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January 1, 2013

Aortic valve sparing operations demonstrated excellent long-term durability, with an overall survival of 69.3% and freedom from reoperation of 94.2% at 20 years.

View Full Paper

Ask AI

Bookmark

Population

Patients undergoing aortic valve sparing operations at a single institution

Design

Case_series

Follow-up

20 years

Key result

Aortic valve sparing operations demonstrated excellent long-term durability, with an overall survival of 69.3% and freedom from reoperation of 94.2% at 20 years.

Authors

TDTirone E. David

Discussion

Member takes

Overview

Supports aortic valve sparing durability in selected patients; single-center data leaves generalizability open.

Study Design

Type

Cohort (n=374)

Multicenter

Structured PICO

Population

374 consecutive patients undergoing aortic valve sparing operations (reimplantation or remodeling) for aortic root aneurysm or insufficiency, followed for a mean of 7.2 years.

Intervention

Aortic valve sparing operations (reimplantation of the aortic valve and remodeling of the aortic root)

Outcome

Clinical outcomes at 20 years

This presentation summarizes a 20-year single-center clinical experience with aortic valve sparing operations.

Limitations

Single-center observational design
Potential selection bias in the choice between reimplantation and remodeling procedures
Lack of statistical power to detect significant differences in late aortic insufficiency between techniques

Cite This Study

synapsesocial.com/papers/6a20e0c7dc4e16663149d236 https://doi.org/10.3978/j.issn.2225-319x.2012.11.15

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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