Key points are not available for this paper at this time.
Insufficient concern has been expressed about the development and incidence of unexpected adverse reactions to drugs given prophylactically over many years in attempts to reduce the risks of coronary and cerebrovascular diseases in predisposed but otherwise healthy persons. It has been assumed that the risks associated with drug treatment are low because they relate mostly to predictable minor side effects or idiosyncratic reactions, but when reactions include increased morbidity and mortality, a reappraisal is necessary; the risks involved in correcting risk must be compared with the risk of the disease in question.It may seem to be stating the obvious . . .
Michael F. Oliver (Thu,) studied this question.