Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
October 1, 2004Journal of Cardiovascular Electrophysiology

Biophysics of Ablation:

View Full Paper
Ask AI
Bookmark
Share

Why the study?

How do different radiofrequency catheter ablation technologies affect tissue lesion surface area and depth?

Population

Tissue undergoing radiofrequency catheter ablation

Design

Review

Authors

DHDavid E. Haines

Discussion

Loading...

Member takes

Overview

Catheter selection may influence lesion geometry during RF ablation; literature review leaves open whether these differences affect clinical outcomes.

Key Points

  • The aim is to understand the biophysical mechanisms of tissue response during radiofrequency catheter ablation.
  • Three assumptions about RF ablation were evaluated: thermal mediation of tissue injury, predictable heat transfer, and efficacy of large lesion technologies.
  • Predictions regarding these assumptions were discussed and tested.
  • The study provided insights into the temperature thresholds for tissue injury.
  • Tissue injury occurs reproducibly at temperatures around 50 degrees C.
  • Heat transfer in tissue was confirmed to be a predictable phenomenon.
  • Greater surface area and depth of ablation were achieved with specific catheter designs, including a 10-mm tip and Chilli cooled ablation catheter.

Structured PICO

How do different radiofrequency catheter ablation technologies affect tissue lesion surface area and depth?

P
Population
Tissue undergoing radiofrequency catheter ablation
I
Intervention
Radiofrequency catheter ablation using different delivery systems (10-mm tip vs Chilli cooled ablation catheter)
O
Outcome
Tissue injury characteristics (surface area and depth of ablation)surrogate

Different large-lesion RF ablation technologies have distinct biophysical effects, with 10-mm tips creating wider lesions and cooled catheters creating deeper lesions.

Cite This Study

David E. Haines (2004) studied this question.

synapsesocial.com/papers/6a20e7a9e2d1a39857ecc331https://doi.org/10.1046/j.1540-8167.2004.15102.x
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Tissue Heating During Radiofrequency Catheter Ablation: A Thermodynamic Model and Observations in Isolated Perfused and Superfused Canine Right Ventricular Free Wall1989 · 438 citations
  2. 2Observations on electrode-tissue interface temperature and effect on electrical impedance during radiofrequency ablation of ventricular myocardium.1990 · 319 citations
  3. 3<b>Effects of Heating with Radiofrequency Power on Myocardial Impulse Conduction</b>: Is Radiofrequency Ablation Exclusively Thermally Mediated?1996 · 35 citations
  4. 4Comparison of In Vivo Tissue Temperature Profile and Lesion Geometry for Radiofrequency Ablation With a Saline-Irrigated Electrode Versus Temperature Control in a Canine Thigh Muscle Preparation1995 · 627 citations
  5. 5Nonuniform Heating During Radiofrequency Catheter Ablation With Long Electrodes1997 · 69 citations