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March 10, 1995Science

Control of IκB-α Proteolysis by Site-Specific, Signal-Induced Phosphorylation

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Authors

KBKeith BrownUniversity of WashingtonSGSusan M. GerstbergerNational Institutes of HealthLCLouise CarlsonIndiana University Health

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Cite This Study

Brown et al. (1995) studied this question.

synapsesocial.com/papers/6a20e8b7e72f0fa382ecbb73https://doi.org/10.1126/science.7878466
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Activation of NF-kappa B requires proteolysis of the inhibitor I kappa B-alpha: signal-induced phosphorylation of I kappa B-alpha alone does not release active NF-kappa B.1995 · 246 citations
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  3. 3Amino Acid Sequences Common to Rapidly Degraded Proteins: The PEST Hypothesis1986 · 2,576 citations
  4. 4High resolution two-dimensional electrophoresis of proteins.1975 · 19,370 citations
  5. 5Human T-Cell Leukemia Virus Type I Tax Activation of NF-ΝB/Rel Involves Phosphorylation and Degradation of IΙBκ and RelA (p65)-Mediated Induction of the italic to c-rel Gene1994 · 175 citations