Why the study?
Does anticoagulant therapy reduce overall mortality in patients after acute myocardial infarction?
Population
1,136 patients with acute myocardial infarction admitted to the Bronx Municipal Hospital Center
Comparison
Anticoagulant therapy vs Control (no anticoagulant therapy)
Design
Cohort
Authors
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Supports hypothesis of sex-specific post-MI anticoagulant effects; leaves open confirmation before any practice change.
Does anticoagulant therapy reduce overall mortality in patients after acute myocardial infarction?
Anticoagulant therapy after acute myocardial infarction appears to reduce mortality primarily in women and specific subgroups of men, suggesting age, sex, and infarct severity should guide its use.
Arnold Drapkin (1972) studied this question.
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