Population
103 individuals, comprising 36 patients with post-polio syndrome and 67 controls.
Design
Case-control
Authors
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May support persistent poliovirus in post-polio syndrome; leaves open need for prospective trials before any clinical implications.
Patients with post-polio syndrome exhibit an intrathecal immune response against poliovirus, suggesting that persistent or recurrent infection may contribute to the recrudescence of muscle weakness.
Sharief et al. (1991) studied this question.
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