Why the study?
Does pretreatment with adult progenitor cells protect myocardium from acute ischemic damage and improve postischemic recovery?
Population
Preclinical model of myocardial ischemia (hearts)
Comparison
Pretreatment with adult progenitor cells from… vs Control hearts and differentiated cell control
Design
Preclinical
Authors
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Hypothesis-generating for progenitor cell cardioprotection; leaves open translation to clinical ischemia-reperfusion injury.
Does pretreatment with adult progenitor cells protect myocardium from acute ischemic damage and improve postischemic recovery?
Pretreatment with adult progenitor cells immediately before an ischemic event improves postischemic myocardial recovery and reduces proinflammatory signaling in a preclinical model.
Wang et al. (2006) studied this question.
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