Why the study?
Does artificial atrial and ventricular pacing improve control of arrhythmias in patients with refractory arrhythmias?
Does artificial atrial and ventricular pacing improve control of arrhythmias in patients with refractory arrhythmias?
Artificial pacing provides a critical mechanism to prevent life-threatening arrhythmias and allows for concomitant antiarrhythmic drug use in refractory cases.
Answers are grounded in this paper and cite their sources.
Should not yet change practice for refractory arrhythmias; leaves open pacing role pending prospective trials.
Five patients with various types of arrhythmias refractory to standard therapeutic agents are presented, and the therapeutic approach to the control of these arrhythmias is outlined. The possible electrophysiologic mechanisms operative are discussed in detail. The most important aspect of artificial pacing is the prevention of arrhythmias that are incompatible with life: ventricular asystole and ventricular fibrillation. Important additional benefits of pacing include the control of less threatening but symptomatic tachyarrhythmias and bradyarrhythmias and the preservation of the best hemodynamic and electrophysiologic relationships possible. Pacing allows the concomitant use of drugs to control tachyarrhythmias without fear of suppressing intrinsic impulse formation and producing asystole. Because of the varied modes of pacing available, it is imperative that each patient be evaluated carefully and that a type of pacing be selected that best serves his needs.
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Zipes et al. (1969) studied this question.
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