Why the study?
Does postprandial insulin lispro administration improve glycemic control compared to preprandial administration in patients with Type 1 diabetes?
Population
31 patients with Type 1 diabetes
Comparison
Postprandial injection of bolus insulin lispro… vs Preprandial injection of bolus insulin lispro…
Design
RCT
Follow-up
6 months (3 months per treatment period)
Authors
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Postprandial lispro yields slightly poorer HbA1c than preprandial; reinforces pre-meal dosing preference in type 1 diabetes.
Does postprandial insulin lispro administration improve glycemic control compared to preprandial administration in patients with Type 1 diabetes?
Postprandial insulin lispro is an acceptable regimen but results in slightly poorer long-term glycemic control compared to preprandial administration in Type 1 diabetes.
Schernthaner et al. (2004) studied this question.
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