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August 17, 2022BMC Public HealthOpen Access

Male sex was significantly associated with a higher prevalence of hypertriglyceridemia compared to female sex (AOR 2.15) among Royal Thai Army personnel.

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Why the study?

Hypertriglyceridemia is independently associated with an increased risk of ASCVD, but its prevalence and associated behavioral and cardiometabolic risk factors among Royal Thai Army personnel required evaluation.

Population

257,683 active-duty Royal Thai Army personnel aged 35-60 years

Comparison

Behavioral and cardiometabolic risk factors for hypertriglyceridemia

Design

Serial cross-sectional study

Key result

Male sex was significantly associated with a higher prevalence of hypertriglyceridemia compared to female sex (AOR 2.15) among Royal Thai Army personnel.

Authors

BSBoonsub SakboonyaratJPJaturon PooviengKJKanlaya Jongcherdchootrakul

Discussion

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Overview

Suggests sex-specific screening in military cohorts; leaves open causal inference and generalizability beyond this population.

Study Design

Type

Cross-Sectional (n=257,683)

Multicenter

Yes

Structured PICO

P
Population
257,683 active-duty Royal Thai Army personnel aged 35-60 years were evaluated in a serial cross-sectional study to determine the prevalence and risk factors of hypertriglyceridemia from 2017 to 2021.
O
Outcome
Prevalence of hypertriglyceridemia (fasting triglyceride ≥150 mg/dL) and its behavioral and cardiometabolic risk factorssurrogate

Main Result

Odds Ratio: 2.15 (95% CI 2.07–2.23)

Absolute Event Rate: 44.3% vs 19.9%

p-value: p=<0.001

Hypertriglyceridemia is highly prevalent among Royal Thai Army personnel, particularly in males and those with cardiometabolic and behavioral risk factors like smoking, alcohol consumption, and sedentary behavior.

Limitations

  • Serial cross-sectional design cannot establish causality
  • Predominantly male population limits generalizability
  • Missing data for some variables like fasting plasma glucose, exercise, smoking, and alcohol
  • Broad categorization of smoking and alcohol consumption without intensity details
  • Lack of data on waist circumference and abdominal obesity

Cite This Study

Sakboonyarat et al. (2022) conducted a cross-sectional in Hypertriglyceridemia (n=257,683). Male sex vs. Female sex was evaluated on Hypertriglyceridemia prevalence (AOR 2.15, 95% CI 2.07-2.23, p=<0.001). Male sex was significantly associated with a higher prevalence of hypertriglyceridemia compared to female sex (AOR 2.15) among Royal Thai Army personnel.

synapsesocial.com/papers/6a20ef0d8446b104fdecc447https://doi.org/10.1186/s12889-022-13992-2
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Elevated Triglyceride Level Is Independently Associated With Increased All-Cause Mortality in Patients With Established Coronary Heart Disease2016 · 185 citations
  2. 2Heart Rate, Life Expectancy and the Cardiovascular System: Therapeutic Considerations2015 · 1,944 citations
  3. 3Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study2004 · 12,114 citations
  4. 4Prevalence and associated factors of ischemic heart disease (IHD) among patients with diabetes mellitus: a nation-wide, cross-sectional survey2018 · 64 citations
  5. 5Hyperlipidemia Disrupts Cerebrovascular Reflexes and Worsens Ischemic Perfusion Defect2013 · 65 citations