Key result
Normal pregnancy is associated with significant electrocardiographic changes, including an increase in mean heart rate to 95.75 bpm in the third trimester compared to 76.01 bpm in non-pregnant controls.
Why the study?
Does normal pregnancy alter electrocardiographic parameters compared to nonpregnant women?
Cross-Sectional (n=200)
Yes
Does normal pregnancy alter electrocardiographic parameters compared to nonpregnant women?
Absolute Event Rate: 95.75% vs 76.01%
p-value: p=<0.0001
Normal pregnancy induces significant physiological ECG changes, including increased heart rate, left axis deviation, and QTc prolongation, which must be recognized as normal adaptations to avoid misdiagnosis of heart disease.
Authors
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Supports avoiding misdiagnosis by recognizing normal pregnancy ECG adaptations; leaves open generalizability pending longitudinal data.
Madras et al. (2015) conducted a cross-sectional in Normal pregnancy (n=200). Normal pregnancy vs. Non-pregnant women was evaluated on Mean ECG heart rate (beats per minute) in the third trimester (p=<0.0001). Normal pregnancy is associated with significant electrocardiographic changes, including an increase in mean heart rate to 95.75 bpm in the third trimester compared to 76.01 bpm in non-pregnant controls.
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