Computational modeling demonstrates that vector loops can predict local propagation direction in atrial tissue, though accuracy decreases from 5% error in straight fibers to 14% in curved fibers.
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Vector loop predictions warrant caution in curved fibers; leaves open in vivo testing for arrhythmia mapping applications.
In this preliminary study we examined the effects of fiber curvature on the vector loops calculated in the extracellular field. An interconnected cable model of a two dimensional sheet of atrial tissue was used to model propagation. Activation was simulated for sheets of tissue, with both curved and straight fibers. The resultant extracellular field and vector loops were then calculated for both cases. Consistent with previous work, we found that the vector loop can be used to predict the local direction of propagation to within 5% for the case of straight fibers. In the case of curved fibers the accuracy is reduced somewhat (maximum error of 14%).
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Plank et al. (2005) studied Cardiac tissue modeling. Curved fibers vs. Straight fibers was evaluated on Accuracy of vector loop to predict local direction of propagation.
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