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March 23, 2019Journal of the American Geriatrics SocietyOpen Access

Depressive Symptoms and Total Healthcare Costs: Roles of Functional Limitations and Multimorbidity

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Key result

Mild depressive symptoms in older women were associated with higher subsequent total healthcare costs compared to little or no symptoms (cost ratio 1.34; 95% CI 1.14-1.59).

Why the study?

Depressive symptoms can be both a cause and a consequence of functional limitations and medical conditions, prompting investigation into their association with subsequent total healthcare costs in older women after accounting for functional limitations and multimorbidity.

Are depressive symptoms associated with higher subsequent total healthcare costs in older community-dwelling women?

Population

2508 community-dwelling women (mean age = 79.4 years) across four US sites

Comparison

Mild or moderate to severe depressive symptoms vs little or no depressive symptoms

Design

Prospective cohort study

Follow-up

12 months

Authors

JSJohn T. SchousboeHealthPartnersTVTien VoUniversity of Wisconsin–MadisonAKAllyson M. KatsUniversity of Minnesota

Discussion

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Member takes

Implication

May flag higher costs in older women; leaves open whether treating symptoms reduces expenditures.

Study Design

Type

Cohort (n=2,508)

Multicenter

Yes

Structured PICO

Are depressive symptoms associated with higher subsequent total healthcare costs in older community-dwelling women?

P
Population
2,508 community-dwelling older women (mean age 79.4 years) with linked Medicare claims data, followed for 12 months to assess healthcare costs.
E
Exposure
Mild (GDS score = 2-5) or moderate to severe (GDS score = 6 or more) depressive symptoms
C
Comparator
Little or no depressive symptoms (GDS score = 0-1)
O
Outcome
Total direct healthcare costs during the 12 months following the Y10 examination

Main Result

Effect estimate: cost ratio 1.34 (95% CI 1.14-1.59)

Absolute Event Rate: 7871% vs 4654%

Even mild depressive symptoms in older community-dwelling women are associated with significantly higher subsequent healthcare costs, partially driven by functional limitations and multimorbidity.

Cite This Study

Schousboe et al. (2019) conducted a cohort in Depressive symptoms (n=2,508). Depressive symptoms vs. Little or no depressive symptoms was evaluated on Total direct healthcare costs during the 12 months following the examination (cost ratio 1.34, 95% CI 1.14-1.59). Mild depressive symptoms in older women were associated with higher subsequent total healthcare costs compared to little or no symptoms (cost ratio 1.34; 95% CI 1.14-1.59).

synapsesocial.com/papers/6a20fc83d6f0ec57f816d2b9https://doi.org/10.1111/jgs.15881
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Impact of Depression on Health Care Utilization and Costs among Multimorbid Patients – Results from the MultiCare Cohort Study2014 · 122 citations
  2. 2Depression treatment decreases healthcare expenditures among working age patients with comorbid conditions and type 2 diabetes mellitus along with newly-diagnosed depression2016 · 24 citations
  3. 3Using an annual over-75 health check to screen for depression: validation of the short geriatric depression scale (GDS15) within general practice1999 · 107 citations
  4. 4Accuracy of the 15-item Geriatric Depression Scale (GDS-15) in a community-dwelling oldest-old sample: the Pietà Study2017 · 72 citations