Key result
Balloon mitral valvuloplasty with JOMIVA balloon in pregnant women resulted in a post-procedure mean mitral gradient of 5 mmHg, with no cases requiring mitral valve replacement or causing systemic embolism.
Why the study?
Does over the wire Balloon Mitral Valvuloplasty with JOMIVA balloon improve immediate clinical and echocardiographic outcomes in pregnant women with significant rheumatic mitral stenosis?
Cohort
No
Does over the wire Balloon Mitral Valvuloplasty with JOMIVA balloon improve immediate clinical and echocardiographic outcomes in pregnant women with significant rheumatic mitral stenosis?
Over the wire BMV with JOMIVA balloon appears safe and effective for treating significant rheumatic mitral stenosis during pregnancy, providing good symptomatic improvement without adverse fetal outcomes.
May support JOMIVA BMV in pregnant rheumatic MS; leaves open randomized confirmation before practice change.
INTRODUCTION: Rheumatic mitral stenosis is the most common Valvular Heart Disease encountered during pregnancy. Balloon Mitral Valvuloplasty (BMV) is one of the treatment option available if the symptoms are refractory to the medical management and the valve anatomy is suitable for balloon dilatation. BMV with Inoue balloon is the most common technique being followed worldwide. Over the wire BMV is a modified technique using Joseph Mitral Valvuloplasty (JOMIVA) balloon catheter which is being followed in certain centres. AIM: To assess the immediate post procedure outcome of over the wire BMV with JOMIVA balloon. MATERIALS AND METHODS: Clinical and echocardiographic parameters of pregnant women with significant mitral stenosis who underwent elective BMV with JOMIVA balloon in our institute from 2005 to 2015 were analysed retrospectively. Severity of breathlessness (New York Heart Association Functional Class), and duration of pregnancy was included in the analysis. Pre procedural echocardiographic parameters which included severity of mitral stenosis and Wilkin's scoring were analysed. Clinical, haemodynamic and echocardiographic outcomes immediately after the procedure were analysed. RESULTS: as assessed by echocardiography. Post procedure mean gradient across the mitral valve as assessed by echocardiography was 5 mmHg. Two patients had moderate to severe mitral regurgitation after the procedure and the rest had either no mitral regurgitation or mild mitral regurgitation after the procedure. None of the patients warranted mitral valve replacement after BMV. No patients had any manifestations of systemic embolism like cerebrovascular accident or limb ischemia after the procedure. None of the patients had preterm delivery or adverse fetal outcome during index hospitalisation. CONCLUSION: Over the wire BMV is safe and effective method during pregnancy. The results are comparable to that of Inoue technique. BMV offers a good symptomatic improvement in pregnant women presenting with symptoms of pulmonary congestion because of Rheumatic mitral stenosis.
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Shanmuga Sundaram Rathakrisnnan (2017) conducted a cohort in Rheumatic mitral stenosis during pregnancy. Balloon Mitral Valvuloplasty with JOMIVA balloon was evaluated on Immediate clinical, haemodynamic and echocardiographic outcomes. Balloon mitral valvuloplasty with JOMIVA balloon in pregnant women resulted in a post-procedure mean mitral gradient of 5 mmHg, with no cases requiring mitral valve replacement or causing systemic embolism.
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