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P-dendrimers appear to be excellent candidates as transfecting agents after positively charged functions are grafted at their periphery. Five different generations of protonated dendrimers (1-[G1] to 1-[G5]) and the corresponding methylated series (2-[G1] to 2-[G5]) (two examples are shown here) have been examined as transfecting agents of the luciferase gene within 3T3 cells.
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Loup et al. (1999) studied this question.
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