Key result
An altered sleep and wake cycle can reverse the typical circadian variation of variant angina, causing chest pain attacks to occur during the daytime rather than early morning.
Case Report (n=1)
No
This case suggests that alterations to the sleep-wake cycle can shift the circadian variation of variant angina attacks.
Answers are grounded in this paper and cite their sources.
Altered sleep-wake cycles may shift variant angina timing; this case report leaves open broader applicability and needs prospective validation.
It is known that there is a marked variation in the frequency of variant angina attacks according to the circadian rhythm. The attack frequency is usually highest in the early morning and lowest in the afternoon. We describe here a middle-aged woman with variant angina whose chest pain occurred only during daytime. Because of her job, she sleeps from noon to 6 pm, and she experienced chest pain only during 2 to 3 pm. These findings suggest that the alterations to the sleep and wake cycle can affect the circadian variation of variant angina. (Korean Circ J 2008;38:66-68)
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Min et al. (2008) conducted a case report in Variant angina (n=1). Altered sleep and wake cycle was evaluated on Timing of variant angina attacks. An altered sleep and wake cycle can reverse the typical circadian variation of variant angina, causing chest pain attacks to occur during the daytime rather than early morning.
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