Why the study?
Does external electrical cardioversion reduce Brain Natriuretic Peptide (BNP) plasma levels in patients with chronic non-valvular atrial fibrillation without clinical heart failure?
Does external electrical cardioversion reduce Brain Natriuretic Peptide (BNP) plasma levels in patients with chronic non-valvular atrial fibrillation without clinical heart failure?
Restoration of sinus rhythm via electrical cardioversion significantly reduces BNP levels in patients with lone atrial fibrillation, suggesting that AF intrinsically induces asymptomatic cardiac alteration independent of ventricular rate.
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Suggests AF may induce subclinical cardiac strain independent of HF; hypothesis-generating for rhythm control in lone AF.
Jourdain et al. (2002) studied this question.
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