Poor self-rated health was independently associated with a higher risk of incident atrial fibrillation compared to good self-rated health (adjusted HR 1.85) over a median follow-up of 11 years.
Cohort (n=9,895)
Yes
Does poor self-rated health predict incident atrial fibrillation in the general population?
Poor self-rated health is independently associated with a higher risk of developing incident atrial fibrillation in the general population, though it adds only marginal predictive value to conventional risk factors.
Hazard Ratio: 1.85 (95% CI 1.19–2.87)
Absolute Event Rate: 1.9% vs 1.2%
p-value: p=0.01
The association between self-rated health (SRH) and the development of atrial fibrillation (AF) in the general population remains underexplored. We reviewed the data of 9,895 participants in the Ansung-Ansan cohort study, a community-based Korean study. SRH was categorised as 'poor', 'fair', or 'good'. A newly developed AF was identified through biennial electrocardiography examinations and/or a self-reported history of physician-determined diagnoses. Over a median follow-up of 11 years, 149 patients (1.5%) developed AF. Compared with the 'good' group, the 'poor' group exhibited a higher risk of incident AF (adjusted hazard ratio, 1.85; 95% confidence interval, 1.19-2.87). Old age, female sex, lower educational level, smoking, cardiovascular diseases (hypertension, diabetes mellitus, and coronary artery disease), and inflammation were associated with 'poor' SRH. Along with SRH, age, male sex, urban residence, hypertension, and myocardial infarction were also associated with a higher risk of incidental AF. The combined model, which included conventional risk factors and SRH, demonstrated a marginally improved performance in predicting incident AF (concordance index: 0.704 vs. 0.714, P = 0.058). Poor SRH is independently associated with the development of AF in Korean adults. However, it plays a limited role in AF surveillance when combined with conventional AF risk factors.
Lee et al. (Sun,) conducted a cohort in Incident atrial fibrillation (n=9,895). Poor self-rated health vs. Good self-rated health was evaluated on Incident atrial fibrillation (HR 1.85, 95% CI 1.19-2.87, p=0.01). Poor self-rated health was independently associated with a higher risk of incident atrial fibrillation compared to good self-rated health (adjusted HR 1.85) over a median follow-up of 11 years.