Key result
Retrograde venous ethanol infusion successfully and safely abolished deep-seated left ventricular summit premature ventricular contractions unresponsive to radiofrequency ablation.
Why the study?
LV summit PVCs are often unresponsive to RF ablation, making retrograde venous ethanol infusion a potential alternative.
Does retrograde venous ethanol infusion safely and effectively treat deep-seated left ventricular summit premature ventricular contractions unresponsive to radiofrequency ablation?
Case Report (n=1)
Does retrograde venous ethanol infusion safely and effectively treat deep-seated left ventricular summit premature ventricular contractions unresponsive to radiofrequency ablation?
Retrograde venous ethanol infusion can effectively treat deep-seated LV summit PVCs refractory to RF ablation, creating an intramural scar that can be characterized by MRI.
Answers are grounded in this paper and cite their sources.
May support retrograde venous ethanol for RF-refractory LV summit PVCs; leaves open need for prospective validation.
Left ventricular (LV) summit premature ventricular contractions (PVCs) are often unresponsive to radiofrequency (RF) ablation. Retrograde venous ethanol infusion (RVEI) can be a valuable alternative in this scenario. A 43-year-old woman without structural heart disease presented with LV summit PVCs unresponsive to RF ablation because of their deep-seated origin. Unipolar pace mapping performed through a wire inserted into a branch of the distal great cardiac vein (GCV) demonstrated 12/12 concordance with the clinical PVCs thus indicating close proximity to PVCs' origin. RVEI abolished the PVCs without complications. Subsequently, magnetic resonance imaging (MRI) evidenced an intramural myocardial scar produced by ethanol ablation. In conclusion, RVEI effectively and safely treated PVC arising from a deep site in the LVS. The scar provoked by chemical damage was well characterized by MRI imaging.
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Limite et al. (2023) conducted a case report in Left ventricular summit premature ventricular contractions (n=1). Retrograde venous ethanol infusion was evaluated on Abolition of premature ventricular contractions and scar assessment. Retrograde venous ethanol infusion successfully and safely abolished deep-seated left ventricular summit premature ventricular contractions unresponsive to radiofrequency ablation.
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