Key result
About 32.6% of incident ischemic strokes were associated with atrial fibrillation, and despite increases over time, rates of premorbid anticoagulation remained low.
Why the study?
Prevalence of AF is increasing, but its impact on the overall burden of stroke and the proportion attributable to under-anticoagulation remain uncertain.
Systematic Review
Yes
Despite increasing use of anticoagulation, about one-third of incident ischemic strokes remain associated with atrial fibrillation, highlighting a major public health opportunity to improve premorbid anticoagulation.
No takes yet. Share an insight, caveat, or question.
Sustained low premorbid anticoagulation leaves one-third of ischemic strokes AF-associated; extends evidence for intensified AF detection and therapy.
Yiin et al. (2018) conducted a systematic review in Ischemic stroke and atrial fibrillation. Atrial fibrillation was evaluated on Proportion of incident ischemic strokes associated with atrial fibrillation in OXVASC (95% CI 30.5-34.7). About 32.6% of incident ischemic strokes were associated with atrial fibrillation, and despite increases over time, rates of premorbid anticoagulation remained low.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: