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Article1 January 1940THE PATHOGENESIS OF HEMORRHAGE IN ARTIFICIALLY INDUCED FEVERSLOAN J. WILSON, M.D., CHARLES A. DOAN, M.D., F.A.C.P.SLOAN J. WILSON, M.D.Search for more papers by this author, CHARLES A. DOAN, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-13-7-1214 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptArtificially induced fever has attained a definite place among modern therapeutic procedures. Hyperpyrexia, however, is attended by actual, as well as by potential dangers, as is usually the case with any powerful therapeutic agent. Tissue injury from prolonged or excessive exposure to heat has long been recognized. Two of the most constant pathologic findings under such circumstances have been acute liver damage and hemorrhage. In replies to a questionnaire regarding fever therapy, which was sent to physicians by the Council on Physical Therapy, "several reported instances of cerebral hemorrhage."1Five fatalities have been cited by Hartman and Major2, 3and...Bibliography1. Hyperpyrexia produced by physical agents—Report of Council on Physical Therapy, Jr. Am. Med. Assoc., 1934, ciii, 1308-1309. Google Scholar2. HARTMANMAJOR FWRC: Pathological changes resulting from accurately controlled fever, Am. Jr. Clin. Path., 1935, v, 392-410. CrossrefGoogle Scholar3. HARTMAN FW: Lesions of the brain following fever therapy. Etiology and pathogenesis, Jr. Am. Med. Assoc., 1937, cix, 2116-2121. CrossrefGoogle Scholar4. WILBURSTEVENS ELJB: Morbid anatomic changes following artificial fever, with report of autopsies, South. Med. Jr., 1937, xxx, 286-290. CrossrefGoogle Scholar5. BALDWINNELSON WMWC: The histologic effects produced in albino rats by high frequency currents, Proc. Soc. Exper. 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PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byTherapeutic hyperthermiaTHE HÆMORRHAGIC DIATHESIS OF HEATSTROKEPURPURIC CHICKENPOX: REPORT OF A CASE, REVIEW OF THE LITERATURE, AND CLASSIFICATION BY CLINICAL FEATURES*N. DAVID CHARKESThe renal, cardiovascular, hematologic and serum electrolyte abnormalities of heat strokeHeatstroke and jaundiceThe effect of corticotropin (ACTH) and cortisone on idiopathic thrombocytopenic purpura 1 January 1940Volume 13, Issue 7Page: 1214-1229KeywordsFeversHemorrhageHemorrhagic feversHyperthermiaLiverPathogenesisQuestionnaires ePublished: 1 December 2008 Issue Published: 1 January 1940 PDF downloadLoading ...
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