Key result
Daily oral CBD fails to improve fitness, body composition, mental health, or CRP versus placebo.
Why the study?
There is a lack of research on the effects of cannabidiol on health-related fitness, physical activity, cognitive health, psychological wellbeing, and C-reactive protein concentrations in healthy individuals.
Does oral cannabidiol improve health-related fitness, physical activity, cognitive health, psychological wellbeing, and CRP concentrations in healthy adults?
Comparison
Oral capsules of 50 mg of CBD daily vs calorie-matched placebo daily
Design
Randomized trial
Follow-up
8 weeks
Authors
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No benefit from 50 mg daily oral CBD on fitness or mental health in healthy adults; reinforces null effects and directs research to other doses or populations.
RCT (n=48)
randomized
Does oral cannabidiol improve health-related fitness, physical activity, cognitive health, psychological wellbeing, and CRP concentrations in healthy adults?
Eight weeks of 50 mg daily oral cannabidiol supplementation did not significantly alter measures of health-related fitness, mental health, or inflammation in healthy adults, though it may prevent declines in anaerobic fitness.
Flores et al. (2023) conducted an RCT in Healthy adults (n=48). Oral Cannabidiol (CBD) vs. calorie-matched placebo was evaluated on body composition, aerobic fitness, muscular strength, physical activity, cognitive health, psychological wellbeing, and resting CRP concentrations. Eight weeks of 50 mg daily oral CBD did not significantly alter body composition, aerobic fitness, mental health, or resting CRP compared to placebo in 48 healthy adults.
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