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In a series of 500 consecutive autopsies in a Swedish population with a high rate of goiter (29%) the incidence of malignant thyroid tumors was 6.0%. There were 25 papillary, 2 follicular, and 2 medullary carcinomas and 1 non-Hodgkin's lymphoma-immunocytoma. No significant differences in tumor incidence was found between goiter patients and those with normal glands. Notably the tumors occurred more often in men than in women (ratio, 1.5).
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Nielsen et al. (1985) studied this question.
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