Key result
Left atrial deformation assessment may be a useful tool to detect early ultrastructural alterations and guide patient-tailored surgical timing in aortic and mitral valve disease.
Why the study?
Determining optimal surgical timing in aortic and mitral valve disease can be challenging using current symptom and left ventricular dysfunction criteria, prompting evaluation of left atrial function to guide early intervention.
Does the assessment of left atrial function and deformation help guide optimal surgical timing in patients with aortic and mitral valve disease?
Does the assessment of left atrial function and deformation help guide optimal surgical timing in patients with aortic and mitral valve disease?
Answers are grounded in this paper and cite their sources.
Left atrial deformation assessment may help optimize the timing of surgical intervention in patients with asymptomatic or minimally symptomatic aortic and mitral valve disease.
The right management of both mitral and aortic disease can be challenging, especially in asymptomatic patients. The current guidelines recommend valve repair or replacement when symptoms arise or when there is an evident left ventricular dysfunction. However, deciding the optimal surgical timing can be very difficult, since the line between the absence of symptoms and being minimally symptomatic, especially in the elderly, is blurred. Another relevant issue regards the second surgical criterion: operating on a patient with a reduced left ventricular ejection fraction or with a dilated left ventricle might jeopardize the possibility of a fully reverse remodeling of the heart after surgery. In this scenario, the left atrium might play an important role. In particular, left atrial deformation might be a very useful tool to detect early ultrastructural alterations, and help or support guiding a patient-tailored treatment at an early stage, optimizing the outcome in the long term.
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Cameli et al. (2019) conducted a review in Aortic and mitral valve disease. Left atrial deformation assessment was evaluated. Left atrial deformation assessment may be a useful tool to detect early ultrastructural alterations and guide patient-tailored surgical timing in aortic and mitral valve disease.
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