What question did this study set out to answer?

This study aims to evaluate the antibacterial effects of myrcene, camphene, and their combinations with ceftazidime against resistant bacteria.

June 4, 2026

Synergistic potential between camphene, myrcene, and ceftazidime against medically important bacteria

Key Points

This study aims to evaluate the antibacterial effects of myrcene, camphene, and their combinations with ceftazidime against resistant bacteria.
Assessed antibacterial activity using hemolysis assay.
Evaluated combinations of myrcene and camphene with ceftazidime.
Examined membrane involvement and cytoplasmic release of resistant strains.
Demonstrated eightfold reduction in resistance with terpenes combined with ceftazidime.
Terpenes had no hemolytic activity, indicating they are safe for use.
Findings suggest enhanced antibacterial activity against specific resistant strains.

Abstract

AIMS: Bacterial multidrug resistance represents a major global public health challenge, highlighting the need for alternative or complementary therapeutic strategies. This study evaluated the antibacterial effects of myrcene (MYR), camphene (CAM), their combination, and their association with ceftazidime (CAZ). MATERIALS AND METHODS: hemolysis assay. RESULTS: resistance by eightfold. Cytoplasmic release indicated membrane involvement, and terpenes showed no hemolytic activity. CONCLUSIONS: The results indicate that terpenes, particularly in combination with CAZ, may enhance antibacterial activity against specific resistant strains, suggesting a promising adjunctive therapeutic strategy.

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Cite This Study

Coriolano et al. (Tue,) studied this question.

synapsesocial.com/papers/6a2115d7d499ed480b16ee93 https://doi.org/https://doi.org/10.1080/17460913.2026.2678108

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