Synergistic potential between camphene, myrcene, and ceftazidime against medically important bacteria

AIMS: Bacterial multidrug resistance represents a major global public health challenge, highlighting the need for alternative or complementary therapeutic strategies. This study evaluated the antibacterial effects of myrcene (MYR), camphene (CAM), their combination, and their association with ceftazidime (CAZ). MATERIALS AND METHODS: hemolysis assay. RESULTS: resistance by eightfold. Cytoplasmic release indicated membrane involvement, and terpenes showed no hemolytic activity. CONCLUSIONS: The results indicate that terpenes, particularly in combination with CAZ, may enhance antibacterial activity against specific resistant strains, suggesting a promising adjunctive therapeutic strategy.