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June 4, 2026Journal of Basic and Clinical Physiology and Pharmacology

Neurophysiology of abdominal pain: a review of peripheral, spinal, central mechanisms and emerging research trends

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Authors

RRRavindran RevandRKRani Kumari

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Overview

Review outlines mechanisms of visceral pain in abdominal organs, suggesting vital implications for pain management.

Key Points

  • This review aims to explore the neurophysiological pathways involved in the experience of abdominal pain, highlighting interactions at peripheral, spinal, and central levels.
  • Comprehensive literature review on visceral pain mechanisms and pathways
  • Discussion of sensory neuron transduction and pain signal transmission
  • Analysis of clinical practices and necessary diagnostic investigations including biochemical and radiological assessments.
  • Visceral pain is often diffuse and poorly defined due to sparse sensory innervation.
  • Noxious stimuli from abdominal organs are fundamentally different from somatic pain triggers.
  • Understanding these mechanisms is essential for effective clinical management of abdominal pain.

Cite This Study

Revand et al. (2026) studied this question.

synapsesocial.com/papers/6a211670d499ed480b16f5c5https://doi.org/10.1515/jbcpp-2026-0034
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