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Shows targeted therapy enhances tumor regression in cancer, suggesting a novel treatment approach.
induces immunogenic cell death, promotes dendritic-cell maturation, and amplifies T-cell activation, ultimately leading to substantial solid tumor regression (94.4% inhibition in vivo). This work demonstrates that cationic photosensitizer-functionalized bacteria can enhance bacterial tumor targeting and photoimmune therapeutic efficacy, providing a chemically guided strategy for bacteria-based cancer treatment.
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Lei et al. (2026) studied this question.
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