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June 4, 2026The Journal of The Korean Dental Association

IgG4-related disease on parotid gland mimicking pleomorphic adenoma: Report of a case

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Authors

SHSuah HanDLDae Ho LeemJKJeong‐Kui Ku

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Overview

Case report shows diagnostic challenges in distinguishing IgG4-RD from benign tumors in a 66-year-old woman, suggesting the need for careful evaluation.

Key Points

  • This report aims to highlight the diagnostic difficulties in identifying IgG4-related disease as distinct from pleomorphic adenoma.
  • Case report of a 66-year-old female with swelling in the left temporomandibular joint region.
  • Imaging studies included magnetic resonance imaging and ultrasonography-guided fine needle aspiration.
  • Histopathological examination and serum IgG4 level measurement were performed.
  • Histopathological findings revealed a lymphoepithelial cyst with storiform fibrosis and IgG4-positive plasma cells (72/HPF).
  • Elevated serum IgG4 level was noted at 141 mg/dL, confirming the diagnosis of IgG4-RD.
  • The patient was referred for further evaluation and steroid therapy consideration.

Cite This Study

Han et al. (2026) studied this question.

synapsesocial.com/papers/6a211689d499ed480b16f7cdhttps://doi.org/10.22974/jkda.2026.64.5.001
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Also Consider

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  5. 5The “great imitator”: <scp>IgG4</scp>‐related disease of the oral cavity. Two case reports and scoping review2024 · 3 citations