Full process of step-by-step establishment of a standardized methodology for pig burn model

Burns cause severe skin damage and lead to complex complications. Current treatments offer limited relief, prompting the need for new therapies that require suitable animal models. Pig models are widely used due to their skin’s similarity to human skin, but there is a lack of standardized methods for creating these models, which hinders research comparability and evaluation. Our team summarized the specific process for developing porcine burn models, detailing key steps from design to establishment and offering solutions for potential issues. Utilizing this review, we endeavor to furnish researchers with precise guidance in the design and implementation of animal burn models.