Crystallographic and Theoretical Insights into a Fluorogenic Turn-On Probe for Selective Fe³⁺ Detection with Biomolecular Binding and In Vitro Anticancer Studies

Q: What does this research mean for the field?

A newly developed fluorogenic turn-on probe enables selective detection of Fe3+ ions and demonstrates biomolecular binding capabilities along with in vitro anticancer activity. Novelty: ClaimNovelty.METHODOLOGICAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Hazeena Shinziya; A. Das; Sahana Suresh; Paula Brandão; Urmila Saha; Gouri Karan; Sujata Maiti Choudhury; Malay Dolai

doi:10.1039/d6dt01146b

January 1, 2026Dalton Transactions

Crystallographic and Theoretical Insights into a Fluorogenic Turn-On Probe for Selective Fe³⁺ Detection with Biomolecular Binding and In Vitro Anticancer Studies

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Key Points

This research aims to develop a fluorogenic probe for selective detection of Fe³⁺ and evaluate its anticancer effects.
Utilized crystallographic techniques to characterize the probe's binding properties.
Performed in vitro anticancer studies to assess its therapeutic potential.
The fluorogenic probe showed high selectivity for Fe³⁺ with significant binding affinities.
In vitro experiments indicated enhanced anticancer activity at increasing concentrations.

Implication

Demonstrates selective Fe³⁺ detection in vitro, suggesting anticancer potential.

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Cite This Study

Shinziya et al. (2026) studied this question.

synapsesocial.com/papers/6a2116acd499ed480b16fa96 https://doi.org/10.1039/d6dt01146b

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Crystallographic and Theoretical Insights into a Fluorogenic Turn-On Probe for Selective Fe³⁺ Detection with Biomolecular Binding and In Vitro Anticancer Studies

Key Points

Implication

Abstract

Discussion

Cite This Study

Crystallographic and Theoretical Insights into a Fluorogenic Turn-On Probe for Selective Fe³⁺ Detection with Biomolecular Binding and In Vitro Anticancer Studies

Key Points

Implication

Abstract

Discussion

Cite This Study

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