This research aims to explore the abnormal neuronal architecture in the hippocampus associated with SCN1A mutations.
Examination of hippocampal structure in a child with SCN1A mutation
Literature review on hippocampal malformation and its implications
Identified abnormal neuronal architecture in the hippocampus of the child
Suggested a potential role of SCN1A in brain formation based on literature review
Abstract
In a child with a mutation in SCN1A, hippocampus demonstrates abnormal neuronal architecture. This finding and review of the literature suggest a possible role for the channel in brain formation.