Introduction: , have recently emerged as multi drug-resistant (MDR) bacteria worldwide. Consequently, enterococcal infections have become more challenging to treat due to their increased multiple-drug resistance. Studying the genome of an enterococcal isolate and investigating genome changes over time help researchers better understand the development of antimicrobial resistance in bacterial isolates. Materials & Methods: EntfacYE isolate from a human biological sample was assessed. After phenotypic, biochemical,and molecular verifications of the bacterial isolate, the bacterial genome was completely sequenced. Results: In total, the EntfacYE genomic subsystems contained 23 various categories with 46 antimicrobial resistance genes. In the current study, 31 antimicrobial resistance genes were reported in the subsystems, and 15 genes had no subsystems. Genes conferring tetracycline resistance were reported in this study. Increases in the number and type of antimicrobial resistance genes were recorded, indicating that bacteria are becoming rapidly resistant to available antimicrobials. Conclusion: In general, the study of antimicrobial resistance genes in bacteria can be effective in better understanding resistance patterns and mechanisms, which can lead to find novel protocols for limiting spread of antimicrobial resistance in bacteria.
Maryam et al. (Mon,) studied this question.