Endoscopic Full-Thickness Resection of Rectal Gastrointestinal Stromal Tumor With Endoscopic Rectal Reconstruction

Gastrointestinal stromal tumors (GISTs) of the rectum are rare and present unique management challenges due to their proximity to vital pelvic organs. This report describes the case of a 73-year-old man with multiple comorbidities who was diagnosed with a 3.1 cm distal rectal gastrointestinal stromal tumor. Successful exposed endoscopic full-thickness resection was performed resulting in complete excision of the gastrointestinal stromal tumor and complete endoscopic rectal reconstruction was performed using endoscopic overstitch device. This case demonstrates the effectiveness of free hand endoscopic full-thickness resection as a minimally invasive treatment of rectal GISTs and other subepithelial lesions, particularly in patients for whom traditional surgery poses elevated risks.