What question did this study set out to answer?

To characterize the clinical profile and identify risk factors associated with severe adenoviral infection in hospitalized children.

June 4, 2026BMJ Paediatrics OpenOpen Access

Clinical profile and risk factors of severe adenoviral infections among hospitalised children in South India: a cross-sectional study

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Cross-sectional study identifies clinical indicators of severe adenoviral infections in children, suggesting early intervention strategies.

To characterize the clinical profile and identify risk factors associated with severe adenoviral infection in hospitalized children.
Cross-sectional study of children aged <13 with PCR confirmed adenoviral infection from January to December 2023.
Collected clinical, laboratory, and radiological data to assess predictors of severity.
Performed multivariate logistic regression using laboratory parameters converted to binary outcomes.
Out of 88 children, 28 (31.8%) had severe adenoviral infection.
Independent predictors of severity included breathlessness, elevated procalcitonin (≥0.59 ng/mL), elevated SGOT (≥39 U/L), and low hemoglobin (≤11.0 g/dL).
Children with severe disease required significantly greater respiratory support and longer hospital stays; overall mortality was 2.2%.

Abraham et al. (2026) studied this question.

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June 4, 2026BMJ Paediatrics OpenOpen Access

View Full Paper

Ask AI

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Authors

Cross-sectional study identifies clinical indicators of severe adenoviral infections in children, suggesting early intervention strategies.

To characterize the clinical profile and identify risk factors associated with severe adenoviral infection in hospitalized children.
Cross-sectional study of children aged <13 with PCR confirmed adenoviral infection from January to December 2023.
Collected clinical, laboratory, and radiological data to assess predictors of severity.
Performed multivariate logistic regression using laboratory parameters converted to binary outcomes.
Out of 88 children, 28 (31.8%) had severe adenoviral infection.
Independent predictors of severity included breathlessness, elevated procalcitonin (≥0.59 ng/mL), elevated SGOT (≥39 U/L), and low hemoglobin (≤11.0 g/dL).
Children with severe disease required significantly greater respiratory support and longer hospital stays; overall mortality was 2.2%.

Abraham et al. (2026) studied this question.

View Full Paper

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